Journal of Woundcare Handbook

The professional's guide to wound product selection

Integra Dermal Regeneration Template

Integra LifeSciences

Description

A bilayer membrane system for skin replacement. The dermal replacement layer is made of a porous matrix of fibres of cross-linked bovine tendon collagen and glycosaminoglycan (chondroitin-6-sulphate) that are manufactured to have a controlled porosity and defined degradation rate. The collagen-glycosaminoglycan biodegradable matrix provides a scaffold for cellular invasion and capillary growth. The epidermal substitute layer is made of a thin polysiloxane (silicone) layer to control moisture loss from the wound. The silicone outer layer is removed when the dermal skin has regenerated and is replaced with a thin epidermal skin graft.

Indications

Post-excisional treatment of full- and partial-thickness injuries where sufficient autograft is not available at the time of excision or not desirable due to the physiological condition of the patient. Also indicated for use in reconstruction of post-excisional, full-thickness defects of the integument, where there is, in the opinion of the treating surgeon, a potential benefit to the patient by improving the reconstructive outcome or decreasing their mortality/morbidity.

Contraindications

Use of Integra Template is contraindicated in patients with known hypersensitivity to bovine collagen, chondroitin sulphate derived from shark cartilage, or silicone materials. Integra Template should not be used on clinically diagnosed infected wounds.

Price

5×5cm, 10×12.5cm, 10×25cm, 20×25cm, not on Drug Tariff

More on: Cellular, acellular and matrix-like products